In this study, Chuanyu Xue tackles the complex challenge of optimizing Time-Sensitive Networking (TSN) for real-world applications. Using Chameleon's powerful computing resources, he conducts a comprehensive evaluation of 17 scheduling algorithms across 38,400 problem instances. This research not only sheds light on the strengths and weaknesses of various TSN scheduling methods but also demonstrates how large-scale experimentation can drive advancements in network optimization. Readers will gain insights from Xue's journey, including key findings, implementation challenges, and valuable tips for leveraging Chameleon in their own research.